Poor prognosis of childhood acute lymphoblastic leukaemia.
نویسندگان
چکیده
منابع مشابه
Haemoglobin and prognosis in childhood acute lymphoblastic leukaemia.
Two hundred and nine children presenting consecutively with acute lymphoblastic leukaemia to a regional paediatric oncology unit were investigated to determine the prognostic significance of various factors at diagnosis. There was a strong positive correlation between the pretreatment haemoglobin level and the percentage of bone marrow blast cells in S phase of the cell cycle as assessed by flo...
متن کاملPoor prognosis of acute lymphoblastic leukaemia in Asian children living in the United Kingdom.
A study of the results of treatment of acute lymphoblastic leukaemia in Asian (Indian and Pakistani) children living in the United Kingdom showed that they had a poorer prognosis than native white children due mainly to deaths during remission. Similar proportions of Asian and white children suffered relapse. Lower socioeconomic status, poor nutrition, and difficulties in communication may have...
متن کاملVariable detection of myeloid antigens in childhood acute lymphoblastic leukaemia.
AIMS To determine whether the use of different sources of anti-CD13 and anti-CD33 monoclonal antibodies leads to discrepant results in childhood acute lymphoblastic leukaemia (ALL), which might contribute to the wide variation in the reported incidence of myeloid antigen expressing ALL in childhood. METHODS Stored leukaemic cells from 10 children with previously defined myeloid positive ALL w...
متن کاملBone marrow fibrosis in acute lymphoblastic leukaemia of childhood.
A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provid...
متن کاملHypercalcaemia: an unusual presenting feature of childhood acute lymphoblastic leukaemia.
A 3-year-old boy was referred for management of severe symptomatic hypercalcaemia. His parents reported increasing lower limb pain and weakness over the preceding 4 months. Examination indicated a bedbound, pale, irritable child with generalized bony tenderness and peripheral lymphadenopathy; there were no palpable abdominal masses. The serum calcium was 5 3 mmol/l; serum phosphate, alkaline ph...
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ژورنال
عنوان ژورنال: BMJ
سال: 1983
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.286.6375.1437-c